Yes, business.com is generally trustworthy as a legitimate business resource site. Scamadviser and Scam Detector both give it high trust scores (Scam Detector rates it 84/100, tagging it “Authentic” and “Secure”), and Sitejabber shows a 3.7-star rating from 321 reviews, ranking it first among Business News sites.
The main caveat: several reviewers note that filling out forms (like insurance or software quote requests) can trigger a barrage of unsolicited sales calls and emails. So the content and site itself are legitimate, but be cautious about submitting your contact info through their lead-generation forms.